Hong-Hee Kim Selected Research

Bone Resorption

10/2021	Extracellular vesicles derived from the periodontal pathogen Filifactor alocis induce systemic bone loss through Toll-like receptor 2.
1/2020	The dynactin subunit DCTN1 controls osteoclastogenesis via the Cdc42/PAK2 pathway.
1/2018	Gα12 regulates osteoclastogenesis by modulating NFATc1 expression.
2/2017	SOD2 and Sirt3 Control Osteoclastogenesis by Regulating Mitochondrial ROS.
1/2017	Fluvastatin Inhibits Osteoclast Differentiation and Porphyromonas gingivalis Lipopolysaccharide-Induced Alveolar Bone Erosion in Mice.
1/2017	Stimulation of osteoclast migration and bone resorption by C-C chemokine ligands 19 and 21.
12/2015	Adseverin mediates RANKL-induced osteoclastogenesis by regulating NFATc1.
12/2015	Myristoleic acid inhibits osteoclast formation and bone resorption by suppressing the RANKL activation of Src and Pyk2.
3/2015	Caveolin-1 regulates osteoclastogenesis and bone metabolism in a sex-dependent manner.
11/2013	Lipoproteins are an important bacterial component responsible for bone destruction through the induction of osteoclast differentiation and activation.

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Hong-Hee Kim Research Topics

Disease

30	Bone Resorption 10/2021 - 04/2004
9	Inflammation (Inflammations) 01/2022 - 05/2005
8	Neoplasms (Cancer) 02/2021 - 07/2012
8	Osteoporosis 01/2021 - 05/2006
6	Neoplasm Metastasis (Metastasis) 02/2021 - 08/2007
4	Breast Neoplasms (Breast Cancer) 02/2018 - 09/2014
3	Osteolysis 01/2019 - 09/2014
3	Arthritis (Polyarthritis) 03/2018 - 06/2007
2	Alveolar Bone Loss 01/2022 - 01/2017
2	Hypoxia (Hypoxemia) 11/2002 - 01/2002
1	Bites and Stings (Sting) 01/2022
1	Infections 01/2022
1	Periodontitis 01/2022
1	Body Weight (Weight, Body) 01/2021
1	Metabolic Diseases (Metabolic Disease) 10/2019
1	Hypercholesterolemia 01/2017
1	Triple Negative Breast Neoplasms 03/2016
1	Metabolic Bone Diseases (Osteopenia) 01/2016
1	Bacterial Infections (Bacterial Infection) 11/2013
1	Kidney Diseases (Kidney Disease) 09/2013

Drug/Important Bio-Agent (IBA)

7	CytokinesIBA 10/2021 - 08/2004
5	LigandsIBA 02/2018 - 05/2009
3	ElementsIBA 02/2021 - 11/2002
3	ChemokinesIBA 03/2018 - 07/2012
3	Small Interfering RNA (siRNA)IBA 03/2015 - 04/2009
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2009 - 05/2005
3	RANK LigandIBA 09/2008 - 05/2006
2	Toll-Like Receptor 2IBA 10/2021 - 11/2013
2	Hormones (Hormone)IBA 01/2021 - 08/2004
2	CXCR3 ReceptorsIBA 01/2017 - 07/2012
2	CollagenIBA 01/2017 - 06/2007
2	LipopolysaccharidesIBA 01/2017 - 01/2017
2	LipidsIBA 03/2016 - 07/2010
2	EnzymesIBA 01/2016 - 12/2015
2	Dinoprostone (PGE2)FDA Link 09/2014 - 01/2006
2	Estrogens (Estrogen)FDA Link 11/2009 - 10/2009
2	tanshinoneIBA 12/2008 - 05/2004
2	Macrophage Colony-Stimulating FactorIBA 09/2008 - 01/2007
2	Pharmaceutical PreparationsIBA 06/2008 - 08/2007
2	Proteins (Proteins, Gene)FDA Link 05/2008 - 01/2002
2	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2006 - 05/2006
2	AntioxidantsIBA 07/2006 - 05/2006
2	DNA (Deoxyribonucleic Acid)IBA 05/2006 - 11/2002
2	Thioctic Acid (Lipoic Acid)IBA 05/2006 - 01/2006
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2002 - 01/2002
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2022
1	Antiviral Agents (Antivirals)IBA 01/2022
1	InterferonsIBA 01/2022
1	Ligases (Synthetase)IBA 01/2022
1	Deubiquitinating EnzymesIBA 01/2022
1	UbiquitinIBA 01/2022
1	cyclic guanosine monophosphate-adenosine monophosphateIBA 01/2022
1	InflammasomesIBA 01/2022
1	Virulence Factors (Pathogenicity Factors)IBA 10/2021
1	Conditioned Culture MediaIBA 02/2021
1	Connective Tissue Growth FactorIBA 01/2020
1	Transcription Factors (Transcription Factor)IBA 01/2020
1	Anabolic AgentsIBA 10/2019
1	HaptoglobinsIBA 01/2019
1	Acute-Phase Proteins (Acute-Phase Protein)IBA 01/2019
1	Bortezomib (Velcade)FDA Link 09/2018
1	Chemokine ReceptorsIBA 03/2018
1	Succinic Acid (Succinate)IBA 02/2018
1	CalciumIBA 02/2017
1	S100 Proteins (S 100 Protein)IBA 02/2017
1	S100 Calcium-Binding Protein A4IBA 02/2017
1	Fluvastatin FDA Link 01/2017
1	CC ChemokinesIBA 01/2017
1	Collagen Type II (Type II Collagen)IBA 01/2017
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2017
1	AntibodiesIBA 01/2017
1	Chemokine CXCL10IBA 01/2017
1	Epidermal Growth Factor (EGF)IBA 03/2016
1	Protein SIBA 03/2016
1	flotillinsIBA 03/2016
1	Protein Isoforms (Isoforms)IBA 03/2016
1	scinderinIBA 12/2015
1	9-tetradecenoic acidIBA 12/2015
1	Caveolin 1IBA 03/2015
1	A-factor (Streptomyces)IBA 12/2014
1	PPAR gammaIBA 09/2014
1	Vitamin E FDA LinkGeneric 09/2014
1	6- hydroxy- 2,5,7,8- tetramethylchroman- 2- carboxylic acid (Trolox)IBA 09/2014
1	LipopeptidesIBA 11/2013
1	Lipoproteins (Lipoprotein)IBA 11/2013
1	OsteoprotegerinIBA 11/2013
1	Platelet-Derived Growth FactorIBA 09/2013
1	Interleukin-1 (Interleukin 1)IBA 09/2013
1	TrapidilIBA 09/2013
1	Vasodilator Agents (Vasodilators)IBA 09/2013
1	Collagen Type I (Type I Collagen)IBA 07/2012
1	Bone Density Conservation AgentsIBA 03/2012
1	Adenosine Triphosphatases (ATPase)IBA 07/2010
1	CholesterolIBA 07/2010

Therapy/Procedure

4	Ovariectomy (Oophorectomy) 01/2022 - 05/2012
1	Ligation 01/2022
1	Aftercare (After-Treatment) 02/2021
1	Intraperitoneal Injections 02/2018
1	Transplantation 09/2014
1	Therapeutics 03/2012